Pleurothallidinae with more than 5000 species are the most diverse and numerous group of orchids. This subtribe occurs exclusively in tropical America, with a range extending from Florida and the Caribbean on the north to the northern parts of Argentina on the south. Pleurothallids are predominantly epiphytes growing above 1000 m a.sl. Taxonomical studies reveal new species each year. Herein we propose 5 new species representing Stelis, Lepanthes and Muscarella.