The subject of this text Franklin’s lost Expedition of 1845. The lost British exploration expedition to the Arctic, led by captain John Franklin, which left England in 1845 on two ships, HMS „Erebus” and HMS „Terror”. Article attempts to collect and analyze recent research on the reasons for the failure of the research expedition. Bringing closer the theory of lead poisoning as well as challenging it with new research. Locations of shipwrecks and analysis of the reports on the alleged grave of sir John Franklin.